Feb 25, 2013 14:24
11 yrs ago
3 viewers *
Japanese term
United Kingdom
原体
Japanese to English
Science
Genetics
また，先進的な灌流培養技術を確立し，工業化スケールでの遺伝子組換え型TM原体の製造を可能とした。...
TM遺伝子を導入したチャイニーズハムスター卵巣細胞の培養から遺伝子組換え型TM原体の精製までを国内自社工場内で行っている.
This text is about the development and production of recombinant thrombomodulin (TM) as a drug treatment.
Recombinant TM (a membrane protein) is expressed by the cultured Chinese hamster cells transfected with the TM gene, but I'm not sure whether 原体 refers to the expressed protein itself, which would then be turned into a deliverable drug, or to the cells which expresses the protein.
At the moment I am using 'progenitor' for 原体 but I'm not absolutely sure about this.
Only very educated guesses or correct answers please!
TM遺伝子を導入したチャイニーズハムスター卵巣細胞の培養から遺伝子組換え型TM原体の精製までを国内自社工場内で行っている.
This text is about the development and production of recombinant thrombomodulin (TM) as a drug treatment.
Recombinant TM (a membrane protein) is expressed by the cultured Chinese hamster cells transfected with the TM gene, but I'm not sure whether 原体 refers to the expressed protein itself, which would then be turned into a deliverable drug, or to the cells which expresses the protein.
At the moment I am using 'progenitor' for 原体 but I'm not absolutely sure about this.
Only very educated guesses or correct answers please!
Proposed translations
(English)
| 4 +1 | API |
Kara ph.D.
|
| 3 +1 | agent |
David Gibney
|
Proposed translations
+1
6 hrs
Kara ph.D.
United States
United States
Native in Japanese
United States
Pharmacist & Bio Researcher
Native in: Japanese 
Works in: English to Japanese, Japanese to English
Related KudoZ points
:
3
Selected
API
原体 most likely means API (active pharmaceutical ingredient) and is occasionally used as an equivalent term for 原薬 (drug substance), particularly in the context of drug manufacturing process.
3 KudoZ points awarded for this answer.
Comment: "Thanks. After looking up '医薬原体' based on Mami's comment I decided to use 'bulk drug'."
+1
3 hrs
David Gibney
Ireland
Ireland
Native in English
Works in field
Ireland
Professional, punctual translations
Native in: English
Works in: Japanese to English, English to Japanese
agent
It looks like they are talking about the isolation of recombinant thrombomodulin in the final stages and not the progenitor genes. Maybe 原体 could be omitted from the final translation?
Note from asker:
| Thanks for your help. |
Peer comment(s):
| agree |
Chrisso (X)
: 原体 would not need to be translated as it refers to TM
7 hrs
|
|
Thank you!
|
Something went wrong...