Dec 10, 2008 20:41
15 yrs ago
2 viewers *
Spanish term

no se debe a una mutación

Spanish to English Other Genetics
La variación genética presente en las personas centenarias no se deb a una mutación, sino que podria tratarse de un poliformismo en un solo nucleótido.

The genetic variation present in centenarians is not because a mutation, but because of the possibility of a mutation in a single nucleotide.

La construcción de eta aestructura en inglés no me es familiar, además la palbra poliformismo no estoy seguro si se pueda interpretar como mutación.

Discussion

Kate Major Patience Dec 10, 2008:
I'll second that. Good point James. I agree with your suggestion.
James A. Walsh Dec 10, 2008:
Found as opposed to Present I think I would say "The genetic variation FOUND in centenarians..." rather than Present. Just a suggestion.
Suerte ;.)

Proposed translations

10 mins
Selected

it is not caused by a mutation / it is not due to a mutation

ambas opciones son válidas
Peer comment(s):

neutral Kate Major Patience : Yes, and both options have already been posted by Lisa and I, so why not agree with us instead of re-posting our answers! ;D // No worries: welcome on board! Saludos desde Granada. :)
5 mins
Because... I'm new to this and I didn't realise that's what you have to do. Apologies.
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4 KudoZ points awarded for this answer. Comment: "ok"
+1
4 mins

this is not due to / the result of a mutation

-

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Note added at 17 minutos (2008-12-10 20:58:53 GMT)
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“The genetic variation present in centenarians is not the result of a mutation, but could (rather/instead) be due to a single nucleotide polymorphism.”


There is also a genetic link with later onset Alzheimer's disease. It is weaker than the link described above, but is not confined to a few families and it is **not the result of a mutation.**
http://www.alzheimers.org.uk/site/scripts/documents_info.php...

The mechanism of action of the benzimidazoles is to prevent tubulin repolymerisation and resistance has been widely reported to be **due to a Single Nucleotide Polymorphism (SNP)** that causes a single amino-acid change in -tubulin, F200Y.
http://www.bath.ac.uk/bio-sci/research/profiles/wolstenholme...
Peer comment(s):

agree Gilberto Diaz Castro : You wrote them in the right order in the suggestion then changed them. "...is not due to a mutation but could be the result of poliformic changes in a single nucleotide.
8 hrs
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+1
1 min

is not caused by a mutation

ya

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Note added at 4 mins (2008-12-10 20:46:16 GMT)
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...and is more likely to be the result of a single nuceotide polymorphism.

Single nucleotide polymorphism - Wikipedia, the free encyclopediaThis is simply the lesser of the two allele frequencies for single nucleotide polymorphisms[1]. There are variations between human populations, ...
en.wikipedia.org/wiki/Single_nucleotide_polymorphism - 46k - Cached - Similar pages
SNP array - Wikipedia, the free encyclopedia

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Note added at 17 mins (2008-12-10 20:59:10 GMT)
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***single NUCLEOTIDE polymorphism*** (Typo above ;D)
Peer comment(s):

agree James A. Walsh : Spot on in both cases!
22 mins
Thanks James. :)
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