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English to Indonesian: Pulmonary Hypertension in Patients with Treated Pulmonary Tuberculosis: Analysis of 14 Consecutive Cases General field: Medical
Source text - English Pulmonary Hypertension in Patients with Treated Pulmonary Tuberculosis: Analysis of 14 Consecutive Cases
Abstract
Background: Pulmonary tuberculosis (PTB) is an increasing global health problem that continues to cause significant morbidity and mortality. The impact of PTB has been measured in terms morbidity and mortality and little attention has been paid to continuing respiratory disability in those who were cured. Pulmonary hypertension (PHT) is a serious respiratory disability that results from structural
lung damage and chronic hypoxia. This study was conducted to investigate the presence of PHT in a cohort of treated PTB patients who presented with shortness of breath.
Methods: This is a cross-sectional study that included 14 consecutive patients who were cured of PTB and presented with shortness of breath. Demographic and clinical data were recorded for all patients. PHT was diagnosed using Doppler echocardiography.
Results: Fourteen patients who were treated for PTB and were found to have PHT were studied. All patients were sputum smear negative at the time of the study. The mean age (SD) was 43.1 (13.6) and half of the patients were males. The mean number of years since PTB was diagnosed (SD) was 9.4 (10.9). All patients had abnormal chest x-rays. The commonest radiological abnormality was fibrocavitation which occurred in 50% of patients. Estimated pulmonary artery systolic pressure (PASP) of 51 to 80 mm/Hg was found in 9 patients (64.3%) whereas PASP of 40 to 50 mm/Hg was found in 4 patients (28.6%) and one patient had PASP more than 80 mm/Hg.
Conclusions: Different grades of PHT occurred in this cohort of treated PTB patients on average about 9 years after cure. The findings of this study support implementation of strategies for early detection and prevention of PTB. For those who were cured from PTB, longer periods of disability should be implemented in assessment of disease burden.
Translation - Indonesian Hipertensi Pulmonal pada Pasien yang Telah Sembuh dari Tuberkulosis Paru: Analisa dari 14 Kasus Berturut-turut
Abstrak
Latar Belakang Masalah: Tuberkulosis Paru (TB Paru) merupakan masalah kesehatan dunia yang terus menerus meningkat, dan sampai sekarang menyebabkan tingkat kejadian penyakit (morbiditas) dan tingkat kematian (mortalitas) yang signifikan. Dampak dari TB Paru dapat dilihat dari morbiditas dan mortalitasnya, serta kurangnya perhatian yang diberikan kepada masalah pernafasan yang berkelanjutan pada mereka yang telah sembuh. Hipertensi Pulmonal (HP) adalah penyakit pernafasan serius yang diakibatkan oleh kerusakan struktural pada paru-paru dan hipoksia kronis. Penelitian ini dilakukan untuk mengkaji terjadinya HP pada kumpulan pasien dengan kesulitan bernafas yang telah sembuh dari TB Paru.
Metode Penelitian: Penelitian ini merupakan penelitian silang yang menyertakan berturut-turut 14 orang pasien yang telah sembuh dari TB Paru serta memiliki kesulitan dalam bernafas. Para pasien memiliki rekaman demografis dan data klinisnya masing-masing. HP didiagnosa menggunakan ekokardiografi Doppler.
Hasil Penelitian: Keempatbelas pasien yang telah sembuh dari TB Paru dan diketahui memiliki HP tersebut diteliti. Seluruh pasien memiliki Basil Tahan Asam (BTA) negatif pada saat penelitian dilakukan. Umur rata-rata (SD) adalah 43.1 (13.6) dan setengah dari jumlah pasien tersebut berjenis kelamin laki-laki. Jumlah tahun rata-rata sejak didiagnosis TB Paru (SD) adalah 9.4 (10.9). Seluruh pasien memiliki hasil x-ray yang tidak normal pada dadanya. Kelainan radiologi yang paling umum ditemukan adalah terdapatnya ruang/kavitasi yang sudah mengalami pengerasan jaringan ikat fibrosa serta bersifat permanen (fibrocavitation) yang terjadi pada 50% pasien. Perkiraan tekanan sistolik arteri pulmoner/pulmonary artery systolic pressure (PASP) 51-80 mm/Hg ditemukan pada 9 orang pasien (64.3) dimana PASP 40-50 mm/Hg ditemukan pada 4 orang pasien (28.6) dan seorang pasien lagi memiliki PASP lebih dari 80 mm/Hg.
Kesimpulan: Tingkat HP yang berbeda terjadi pada kumpulan pasien TB Paru yang rata-rata telah sembuh selama 9 tahun. Hasil dari penelitian ini menunjang penerapan strategi untuk deteksi dini dan pencegahan TB Paru. Untuk mereka yang telah sembuh dari TB Paru, periode disabilitas yang lebih lama seharusnya diterapkan dalam penilaian beban penyakit.
Kata kunci: tuberkulosis, hipertensi pulmonal, ekokardiografi
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Experience
Years of experience: 12. Registered at ProZ.com: Apr 2013.
I am a professional freelance translator for English and Indonesian language pair with 3 years of experience. Based in Jakarta, Indonesia, I provide written translation, proofreading and localization service.
