Nov 27, 2018 09:07
5 yrs ago
English term

self-looping

English to Russian Science Biology (-tech,-chem,micro-)
AONs are characterized by a sequence that is complementary to a target RNA sequence and by the presence of a stem-loop structure , which is preferably non-complementary to the target RNA.
Such oligonucleotides are referred to as ‘self-looping AONs’

Proposed translations

+1
2 hrs
Selected

с самоформирующейся петлей

https://patents.google.com/patent/WO2017220751A1/en
Another important aspect of the AON of the present invention is that it does not have a portion that is complementary to the target RNA or the RNA region that comprises the target adenosine that allows the AON in itself to fold into an intramolecular hairpin or other type of (stem-) loop structure (herein also referred to as "auto-looping" or "self-looping"), and which may potentially act as a structure that sequesters ADAR.
https://patents.google.com/patent/RU2432165C2/ru
Шпилечная интерферирующая РНК представляет собой отдельную молекулу (например, отдельная олигонуклеотидая цепь), содержащую и смысловую и антисмысловую цепи интерферирующей РНК в виде структуры стебля-петли или шпильки (например, кшРНК). ...
Полученный в результате транскрипт РНК складывается сам с собой с формированием структуры стебля-петли.
Peer comment(s):

agree Vladyslav Golovaty
8 hrs
Спасибо!
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4 KudoZ points awarded for this answer.
4 hrs

образующий петлю

антисмысловой олигонуклеотид, образующий петлю
как вариант
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