Jan 7, 2010 10:01
14 yrs ago
English term

allostery

GBK English to Malay Science Biology (-tech,-chem,micro-)
Definition from Biochemical Society:
Property of some proteins by which spatially separate functional sites in the molecule can communicate with each other via movements transmitted through the structure.
Example sentences:
Oligomerization enables cooperativity between multiple binding sites, a property referred to as allostery or allosteric regulation of enzymes (yet again, single polypeptide, multi-domain proteins show allosteric behavior). (whatislife.com)
The sequential model of allostery holds that subunits are not connected in such a way that a conformational change in one induces a similar change in the others. Thus all enzyme subunits need not exist in the same conformation. (bio-medicine.org)
It also follows that allostery is common and that homologous proteins can have different allosteric mechanisms. (nature.com)
Change log

Jan 6, 2010 15:05: changed "Kudoz queue" from "In queue" to "Public"

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