English to French Other Biology (-tech,-chem,micro-)

The liquid Factor VII composition subjected to nanofiltration comprises one or more Factor VII polypeptides in a suitable solvent.
The solvent is typically water or an aqueous mixture/solution, such as pure water, an aqueous buffer, a water/ethanol mixture, a water/DMSO mixture, or an aqueous salt solution, e.g. saline, a urea solution or guanidine solution.
A suitable aqueous liquid may also comprise a detergent (surfactant).
In interesting embodiments, the liquid Factor VII composition is obtained, or originates, from a cell culture supernatant, e.g. a cell culture supernatant obtained as disclosed in XXX.

In one embodiment, the liquid Factor VII composition is serum-free, i.e. free from animal-derived components.
Thus, the cell cultures may be cultivated in a medium lacking animal derived components.

An attractive variant hereof is the one where the Factor VII polypeptide(s) is/are produced by cell culture in CHO cells, e.g. in CHO cells in a medium free from any components of animal origin, or a medium lacking animal-derived components and lacking proteins ("protein-free").