Based on your description. See page 4 (and others) of https://ec.europa.eu/health/ph_projects/2003/action3/docs/20... .
Please note the low confidence; I do not work in the field.

It's about the effect / dose.

please see

https://journals.lww.com/nuclearmedicinecomm/Abstract/2021/1...

https://pubmed.ncbi.nlm.nih.gov/10328196/



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Note added at 28 Min. (2022-01-29 19:03:41 GMT)
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https://pubmed.ncbi.nlm.nih.gov/10946402/

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Note added at 29 Min. (2022-01-29 19:04:41 GMT)
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or toxin, of course

There may be multiple solutions. I like the dichotomy of "structural toxicity" and "functional toxicity."

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Note added at 3 hrs (2022-01-29 21:58:39 GMT)
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That quote was cut short and the HTML tags are showing, but it should say "structural toxicity" at the end, in parentheses. You will find the sentence in the first article cited (at academic.oup.com).

Paracetamol poisoning
Administration of paracetamol (acetaminophen) has analgetic and antipyretic effect. After trauma paracetamol has an anti-inflammatory activity. It was presumed that paracetamol in therapeutic doses had fewer and more acceptable side-effects than other analgetic drugs such as acetylsalicylic acid and NSAID-drugs. However, in toxic concentrations, paracetamol is more life-threatening. The toxic effects of paracetamol most often occur in the liver and kidneys. Phosphate and lactate turn-over can also be impaired. Paracetamol poisoning can induce temporary liver disfunction or even irreversible liver failure with liver transplantation as the only therapeutic possibility. Chronic alcoholics are especially at risk, as liver damage may occur following paracetamol even in recommended doses. When intoxication with paracetamol is presumed, administration of N-acetylcysteine is vital. N-acetylcysteine therapy should be initiated not later than 15 hours after paracetamol intake. Moreover, the antitoxic effect has been observed even when N-acetylcysteine therapy is initiated 24-36 hours after presumed paracetamol intake. Measures of preventing further absorption of paracetamol from the gastrointestinal tractshould be taken. Activated charcoal should be given if less than two hours have passed since paracetamol intake. Between two and four hours following paracetamol intake gastric lavage should be performed. During the last 10 years the incidence of paracetamol self-poisoning has increased, but death following paracetamol poisoning is relatively constant at around nine per year in Denmark. It is suggested that the incidenceof paracetamol self-poisoning has increased, but death following paracetamol poisoning is relatively constant at around nine per year in Denmark. It is suggested that the incidence of serious cases of paracetamol poisoning could be reduced by simple measures. Special attention should be paid to the risk-group of chronic alcoholics.

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Note added at 4 ώρες (2022-01-29 22:59:49 GMT)
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https://www.google.com/url?sa=t&source=web&rct=j&url=http://...

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Note added at 4 ώρες (2022-01-29 23:08:09 GMT)
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Lesional poisoning / functional poisoning

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Note added at 4 ώρες (2022-01-29 23:10:09 GMT)
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Lesional poisoning / functional poisoning

I gather we are talking about 'UN toxique', not about toxicity: "Un toxique lésionnel entraîne une lésion d'organe (amanite phalloïde, ... L'intoxication par un toxique lésionnel avant l'apparition de signes de gravité ou ... "

Our friend Bruno Mégarbane (repeatedly on TV since the start of the Covid crisis) writes "For LESION-INDUCING POISONs (e.g. acetaminophen [paracetamol]), the antidote should be administered before the organic lesions develop"
https://www.srlf.org/wp-content/uploads/2015/11/0610-Reanima...
But I'm not convinced. I'd already looked for "lesion-inducing TOXIN", to no avail.

The University of Louvain says " the student should be able to distinguish functional and lesional toxins. He should also be able to assess the responsability"
https://uclouvain.be/en-cours-2021-wsbim2246

Ah, here we have a native English-speaker: "LESIONAL TOXINS (paraquat, acetaminophen (paracetamol), colchicine, amatoxins, heavy metals, etc.) induce cellular or organ damage.
https://www.alpfmedical.info/cardiac-output/evaluation-of-se...

Which appears to be plagiarized from the Oxford Textbook of Critical Care
https://books.google.fr/books?id=_YhNEAAAQBAJ&pg=PA1506&lpg=...

There are not a lot of ghits for the expression however...