Glossary entry

Russian term or phrase:

повторное назначение исследуемого лечения vs. возобновление исследуемого лечения

English translation:

repeated administration of the study treatment vs. rechallenge of the study treatment

Added to glossary by Natalia Novichenko
Oct 21, 2021 17:07
2 yrs ago
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Russian term

повторное назначение исследуемого лечения vs. возобновление исследуемого лечения

Russian to English Medical Medical: Pharmaceuticals Clinical trial terminology
These are two separate items listed next to each other, both requiring separate new consent forms.

One guess is that one of them is "rechallenge" and the other is "reinitiation", but which is which? Or is it "continuation" for повторное and "rechallenge" for возобновление? Available study docs indicate no dose ranging, no crossover, no blind, so it doesn't seem to be a matter of reassigning or adjusting the treatment.

PS Source Russian is clearly based on study documents translated from English (possibly badly)
Change log

Oct 26, 2021 07:09: Natalia Novichenko Created KOG entry

Proposed translations

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14 hrs
Selected

repeated administration of the study treatment vs. rechallenge of the study treatment

ИМХО, русский переводчик ошибочно перевел/выбрал вариант из Мультитрана "repeated administration" как "повторное назначение" вместо "многократного применения" (в отличие от однократного применения). Второе - "rechallenge" правильно, у меня есть ICF с таким названием, означает "возобновление лечения после НЯ". Тогда становится понятным, почему это две разные формы ICF.
Note from asker:
Похоже "повторное" на деле "продление" после НЯ или при отсутствии ожидаемого эффекта
Peer comment(s):

agree svetlana cosquéric
2 days 4 hrs
Спасибо, Светлана!
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4 KudoZ points awarded for this answer.
2 hrs

repeated administration of the study treatment vs. resumption of the study treatment

From the linguistic point of view, повторное назначение could be a repeated administration (de novo) whereas возобновление could be the resumption of a halted treatment.
Note from asker:
Linguistically, sure, but in the context of two different actions that each require separate consent forms... just not sure
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