Apr 15, 2021 11:11
3 yrs ago
20 viewers *
English term

pre-disposing recipients

English to Portuguese Medical Medical (general) Clinical trials
Contexto:
The current vaccine research does not indicate significant Th2 responses as **pre-disposing vaccine recipients** to enhanced COVID-19 disease.

Não entendi muito essa parte do **pre-disposing vaccine recipients** ... Ou é burrice ou é cansaço mesmo...

Muito TIA
Proposed translations (Portuguese)
2 prováveis receptores

Discussion

@Marjolein + Sandra Concordo com a vossa leitura. Talvez traduzisse vaccine recipients por vacinados...
Marjolein Snippe Apr 15, 2021:
I missed that, but I see it now! Apologies - told you my brain was dead! Please read my previous post as "I agree with the explanation below"...
expressisverbis Apr 15, 2021:
Marjolein, Está a dizer precisamente aquilo que eu referi antes...
Marjolein Snippe Apr 15, 2021:
pre-dispose = make more likely (in this context) I read this sentence as "The current vaccine research does not indicate that people with a significant Th2 response who receive the vaccine are more likely (because of this Th2 response) to become more seriously ill if and when they contract COVID-19." My brain is dead, so I will not try to suggest a Portuguese translation for now...
expressisverbis Apr 15, 2021:
Pessoas mais predispostas a reagir à vacina, será? Despite expending considerable effort to characterize the nature and extent of the immune responses induced by various vaccine candidates in several different model systems, it remains unclear precisely what sort of immune response is required to convey lasting and complete immunity to RSV without predisposing vaccine recipients to enhanced disease. Because of the marked imbalance between the clinical burden of RSV and the available therapeutic and prophylactic options, development of an RSV vaccine remains an unmet medical need.
https://patents.google.com/patent/US9717787B2/en

https://www.infopedia.pt/dicionarios/ingles-portugues/pre-di...

"Recipients" parece-me ser os candidatos/pessoas que recebem uma vacina.
O sistema de defesa de cada um funciona de forma mais rápida e predisposta ao reagir a uma vacina.
Paulinho Fonseca Apr 15, 2021:
@Marcia, entendo também como '"descarte" dos recipientes de vacinação/vacina'.

Proposed translations

6 hrs
Selected

prováveis receptores

A interpretação que fiz foi a seguinte:

A pesquisa atual de vacinas não traz resultados significativos que demonstrem que as (células) Th2 atuam como prováveis receptores de vacinas contra a COVID-19.
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