Glossary entry (derived from question below)
English term or phrase:
enrichment for CCNE1 overexpression
Spanish translation:
enriquecimiento para la sobreexpresión del [gen] CCNE1
- The asker opted for community grading. The question was closed on 2018-08-18 14:54:08 based on peer agreement (or, if there were too few peer comments, asker preference.)
Aug 15, 2018 10:25
5 yrs ago
4 viewers *
English term
Spain
Also an interpreter (medical, court)
Native in: Spanish 
Works in: English to Spanish, Spanish to English, French to Spanish, and 3 more.
enrichment for CCNE1 overexpression
English to Spanish
Medical
Medical: Pharmaceuticals
clinical trial
Rationale:
• For patients with HGSOC, the BRCA wild-type population has predicted sensitivity to Chk1 inhibition based on enrichment for CCNE1 overexpression through CCNE1 gene amplification and/or mRNA upregulation and/or cyclin E protein overexpression.
• For patients with anogenital cancer, predicted sensitivity to Chk1 inhibition will be based on either HPV positive status, or sponsor’s review of prospective genetic profiling.
Thanks
• For patients with HGSOC, the BRCA wild-type population has predicted sensitivity to Chk1 inhibition based on enrichment for CCNE1 overexpression through CCNE1 gene amplification and/or mRNA upregulation and/or cyclin E protein overexpression.
• For patients with anogenital cancer, predicted sensitivity to Chk1 inhibition will be based on either HPV positive status, or sponsor’s review of prospective genetic profiling.
Thanks
Proposed translations
(Spanish)
| 3 | enriquecimiento para la sobreexpresión del [gen] CCNE1 |
Patricia Patho
|
Proposed translations
4 mins
Patricia Patho
Germany
Germany
Native in Spanish
Specializes in field
Germany
Sworn Translator; BDÜ; Medicine & Law
Native in: Spanish (Variant: Standard-Spain) 
Works in: German to Spanish, English to Spanish, French to Spanish, and 2 more.
Related KudoZ points
:
130
Selected
enriquecimiento para la sobreexpresión del [gen] CCNE1
x
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Note added at 6 mins (2018-08-15 10:31:49 GMT)
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http://ediciones.grupoaran.com/upload/books/XXXIIISETH/109/
[...] y una sobreexpresión moderada de CCNE1 y CCNE2 en [...]
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Note added at 8 mins (2018-08-15 10:33:40 GMT)
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https://www.downciclopedia.org/genetica/peculiaridades-en-el...
«El enriquecimiento ambiental en el modelo transgénico de sobreexpresión de Dyrk1 A no produjo efectos beneficiosos a nivel conductual en ratones macho, posiblemente debido a un aumento del estrés».
--------------------------------------------------
Note added at 6 mins (2018-08-15 10:31:49 GMT)
--------------------------------------------------
http://ediciones.grupoaran.com/upload/books/XXXIIISETH/109/
[...] y una sobreexpresión moderada de CCNE1 y CCNE2 en [...]
--------------------------------------------------
Note added at 8 mins (2018-08-15 10:33:40 GMT)
--------------------------------------------------
https://www.downciclopedia.org/genetica/peculiaridades-en-el...
«El enriquecimiento ambiental en el modelo transgénico de sobreexpresión de Dyrk1 A no produjo efectos beneficiosos a nivel conductual en ratones macho, posiblemente debido a un aumento del estrés».
4 KudoZ points awarded for this answer.
Comment: "perfect"
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