Aug 12, 2018 14:15
5 yrs ago
4 viewers *
Japanese term

メラニンの摘落(てきらく)

Japanese to English Medical Medical (general) Dermatology Term
よろしくお願いいたします。

・・・昔、激しく日に焼けていた、という方の肩や背中にシミともほくろとも区別のつかないような斑点状の色素沈着がよくみられますが、これは、メラニンの摘落(てきらく)というものです。

Discussion

multiverse Aug 15, 2018:
原文がどうも... 質問の原和文を書いた人は医学分野の専門家ではなく、美容師から叩き上げて出世した方のようですので、この場合そのまま英語に訳すのは無理があるようです。

http://www.merryage.net/10kirei/10kirei_top_b011.html
multiverse Aug 14, 2018:
「これは、メラニンの滴落によるものです」 「昔、激しく日に焼けていた、という方の肩や背中にシミともほくろとも区別のつかないような斑点状の色素沈着がよくみられますが、これは、メラニンの摘落(てきらく)というものです。」
上記の原文末尾の表現は、タイトルのように「これはメラニンの滴落によるものです」と書き直す必要があるようでございます。
multiverse Aug 14, 2018:
「定訳は無く様々な表現が使われている?」をクリック して頂きますと例文が表示されます。
multiverse Aug 14, 2018:
"melanin drop-out"とは「メラニンが抜けてしまうこと」みたいよ。 Chronic inflammation, such as in lichen planus, can result in melanin drop-out, especially in persons with pigmented skin.
https://www.sciencedirect.com/.../neuroscience/pigmentation

Proposed translations

-1
8 mins

melanin pigmentation

摘落 is a typo of 滴落, I believe. Please see the website below. You can see abstract both in English and in Japanese
Note from asker:
ご意見ありがとうございます。「様々な表現が使われている」と言いましたが、例えばどんな表現でしょうか??
Peer comment(s):

disagree multiverse : "melanin pigmentation"または"melanin hyper-pigmentation"は「滴落」そのものではなく「滴落」の結果を表す用語。
1 day 18 hrs
Something went wrong...
8 hrs

dropping off of melanine

https://ci.nii.ac.jp/naid/130004473911/
https://www.derm-hokudai.jp/textbook/pdf/2-03.pdf

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Note added at 8時間 (2018-08-12 22:24:38 GMT)
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原文を書いた人は、色素沈着のメカニズムを十分には理解していないように思われます。

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Note added at 8時間 (2018-08-12 22:28:46 GMT)
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drop outの例
https://www.sciencedirect.com/topics/neuroscience/pigmentati...
https://books.google.co.jp/books?id=QnfODgAAQBAJ&pg=PA383&lp...
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Reference comments

1 day 18 hrs
Reference:

定訳は無く様々な表現が使われている?

Pigmentary incontinence is a phenomenon observed in some inflammatory skin disorders. Clinically it may be seen as a slate-colored pigmentation. Histologically it is seen as an accumulation of melanin in the upper dermis. The possible mechanism for development of pigmentary incontinence is discussed based on a review of the literature and electron microscopic studies of fixed drug eruption.
https://www.sciencedirect.com/science/article/pii/S019096228...

Dermal hypermelanosis can be due to the production of melanin by ectopic dermal melanocytes (dermal melanocytosis), or to an abnormal transfer of melanin from epidermal cells to the dermis (pigmentary incontinence).
https://www.google.co.jp/search?biw=678&bih=356&ei=zG9yW_YZg...

leakage in the dermis of epidermal melanin also exists, a form of dermal hypermelanosis called pigmentary incontinence.
www.em-consulte.com/en/article/775853

Dermal melanosis occurs when inflammation disrupts the basal cell layer, releasing melanin pigment, which is subsequently trapped by papillary dermal macrophages; this effect is also known as pigmentary incontinence.
https://www.consultant360.com/content/skin-disorders-older-a...

Histologically, pigmentary incontinence is caused by melanosome translocation from the epidermis to the dermis, usually following dermo-epidermal junction damage.
https://www.cosmetic-medicine.jp/list/strategy.htm
L
eakage in the dermis of epidermal melanin also exists, a form of dermal hypermelanosis called pigmentary incontinence.
https://www.ncbi.nlm.nih.gov/pubmed/23522626

The dead keratinocytes spill their melanin into adjacent dermis in a processcalled pigmentary incontinence, where it is phagocytized by macrophages (melanophages).
https://books.google.co.jp/books?isbn=0323357970


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Note added at 2日 5時間 (2018-08-14 20:01:43 GMT)
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例文を見るには、「定訳は無く様々な表現が使われている?」をクリックしてくださいませ。

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Note added at 2日 16時間 (2018-08-15 07:05:44 GMT)
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Increased dermal pigmentation probably results from a dischargement of the melanin granules into the dermis secondary to melanocyte alterations.
https://www.ncbi.nlm.nih.gov/pubmed/464658
Something went wrong...
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