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Un reciente ensayo aleatorio se realizó en el sistema de salud de Asuntos de Veteranos...
...escalada libre. Además, el 27% de los pacientes fueron dados de alta debido al mal uso/incumplimiento de la toma de los opioides (22)

https://www.researchgate.net/profile/Eddy_Salvador/publicati...

The use of opioid medications for treating chronic noncancer pain is growing; however, there is a lack of good evidence regarding their long-term effectiveness, association with substance abuse, and proper prescribing guidelines. The current study directly compares for the first time in a randomized trial the effectiveness of a conservative, hold the line (Stable Dose) prescribing strategy for opioid medications with a more liberal dose escalation (Escalating Dose) approach. This 2-arm, parallel, randomized pragmatic clinical trial followed 135 patients referred to a specialty pain clinic at a Veterans Affairs Hospital for 12 months (94% male and 74% with musculoskeletal pain).

https://www.ncbi.nlm.nih.gov/pubmed/21111684

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Note added at 1 hr (2017-05-28 15:54:16 GMT)
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You could also use 'liberal dose escalation'.

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Note added at 1 hr (2017-05-28 15:57:47 GMT)
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Page 17

Higher dosages of opioids are associated with higher risk of overdose and death even relatively low dosages (20-50 morphine milligram equivalents (MME) per day) increase risk. Higher dosages haven’t been shown to reduce pain over the long term. One randomized trial found no difference in pain or function between a more liberal opioid dose escalation strategy (with average final dosage 52 MME) and maintenance of current dosage (average final dosage 40 MME).

https://www.justice.gov/file/944121/download

Despite dose escalation of IV fentanyl to 4,500 mcg per day and hydromorphone to 47 mg per day, his acute pain remained uncontrolled. We were surprised to observe that an opiate-naive patient was refractory to the analgesic, sedative, or respiratory depressant effects of 2 IV opiates with liberal dose escalation.

http://www.painmedicinenews.com/Review-Articles/Article/12-1...