Glossary entry

French term or phrase:

syndrome néphrotique pur primitif

English translation:

pure primary nephrotic syndrome

Added to glossary by Michelle Desaintfuscien
Oct 29, 2011 22:38
12 yrs ago
3 viewers *
French term

pur

French to English Medical Medical (general)
List of medical conditions covered by insurance:

- syndrome néphrotique *pur* primitif

The part of this term that is bothering me is "pur". I have found the translation for the rest of the term: "primary nephrotic syndrome" 196 000 Google results

The problem is that when I put "pure" before this term, Google only gives 6 results for "pure primary nephrotic syndrome"

This makes me think that there might be a better translation for "pur" in a medical context...
Proposed translations (English)
5 pure nephrotic syndrome
4 -1 primary nephrotic syndrome with selective proteinuria

Discussion

SJLD Oct 30, 2011:
@Manu haematuria, hypertension, renal failure (decreased GFR) are not "other comorbidities"

Proposed translations

1 hr
Selected

pure nephrotic syndrome

Whatever, I am a fourth year med student and will be a doctor in one year. I know exactly what I'm talking about. I am French native and truly confident with my answer.

I double checked in the Toronto Notes 2011 and in the Harisson Principles of Internal Medicine 18th.
Peer comment(s):

agree SJLD : yes, but you need to translate "primitif" too - primary, idiopathic, of unknown aetiology
8 hrs
disagree Drmanu49 : You are missing the priitif. (Ref. Prof P. Zaoui CHU Grenoble.)
8 hrs
Something went wrong...
3 KudoZ points awarded for this answer. Comment: "Thanks Laurent. In the end, I included the word 'primary' also, just to be sure. "pure primary nephrotic syndrome""
-1
8 mins

primary nephrotic syndrome with selective proteinuria

medecine.sante-dz.org/cours/uro-Nephro/sdnephro.htm
Le syndrome néphrotique est dit : pur si la protéinurie est sélective ... syndromes néphrotiques des amyloses familiales (amylose primitive héréditaire, maladie ...

www.med.univ-montp1.fr/enseignement/.../328_synd-nephro.pdf
Format de fichier: PDF/Adobe Acrobat - Afficher
Retenir la différence essentielle entre syndrome néphrotique et insuffisance rénale. ◆ Distinguer les différences entre SN pur et impur, entre SN primitif et ...

emedicine.medscape.com/article/244631-overview - Traduire cette page
15 Sep 2011 – Nephrotic syndrome is kidney disease with proteinuria, hypoalbuminemia, and edema. ... Primary causes of nephrotic syndrome include the following, ... Proteinuria that is more than 85% albumin is selective proteinuria. ...
Glomerulonephritis | Doctor | Patient UK
www.patient.co.uk › PatientPlus - Traduire cette page
5 May 2011 – Primary glomerulonephritis may be classified according to the clinical ... Clinical features: nephrotic syndrome with selective proteinuria; normal ...

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Note added at 10 heures (2011-10-30 08:41:29 GMT)
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You could add what I first wanted to write "and no other comorbidities".
Peer comment(s):

disagree Laurent Chevrette (X) : 'Pur' simply means that the nephrotic syndrome is ONLY nephrotic (meaning that its clinical and laboratory characteristics are nephrotic only), as compared to a mixed ('impur') syndrome, which has characteristics of both (nephrotique and nephritique).
43 mins
You better check the French definitions IMO. "Pur si la protéinurie est sélective".
neutral SJLD : this almost corresponds to the French definition of "syndrome néphrotique pur" however selective proteinuria is not the only feature - see refs - primitif = primary or idiopathic IOW unknown aetiology
9 hrs
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Reference comments

9 hrs
Reference:

http://medecine.sante-dz.org/cours/uro-Nephro/sdnephro.htm

Un syndrome néphrotique est pathognomonique d'une néphropathie glomérulaire. Il est dit pur s'il ne s'accompagne pas d'hématurie, ni d'hypertension artérielle, ni d'insuffisance rénale et que la protéinurie est sélective, impur dans le cas contraire.

So it is not only the selective proteinuria that deems a PNS "pure" but the absence of haematuria, hypretension and renal failure.

This corresponds to the English definition of "pure nephrotic syndrome" but we do not make the distinction of selective proteinuria.

http://www.uthsc.edu/nephrology/documents/renal-syndromes-gu...

Patients with pure nephrotic syndrome typically have normal glomerular filtration rate, normal blood pressure, normal acid-base status. The edema is a consequence of avid sodium retention by the kidney as a result of enhanced renal tubular sodium reabsorption (particularly in the distal tubule). The retained salt and water is primarily restricted to extracellular fluid volume. Because of decreased plasma oncotic pressure (due to albuminuria), there is disproportionate increase in the size of the interstitial fluid volume. The plasma volume remains normal, until there is
profound hypoalbuminemia (<2g/dl). There may be associated pleural effusions and ascites with severe volume retention. Since intravascular volume remains normal, pulmonary edema is not a feature of nephrotic syndrome. Hypercholesterolemia is frequently present with nephrotic
syndrome.

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Note added at 9 hrs (2011-10-30 08:21:57 GMT)
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MKSAP Review – Glomerular Diseases
medchiefs.bsd.uchicago.edu/.../MKSAPReviewGlomerularDiseases.p...
File Format: Microsoft Powerpoint - Quick View
Pure nephrotic syndrome without hematuria, hypertension, or change in creatinine; Much more common in children; Can be associated with hematologic
Note from asker:
Thanks for the reference info SJLD!
Something went wrong...
12 hrs
Reference:

pure nephrotic syndrome

pure is used in this case, whether with or without quotes. Small number of hits for "pure primary/idiopathic nephrotic syndrome" may just reflect small number of references to pure syndromes and/or the fact that the syndrome in the context is understood to be primary and "primary" is not expressed.

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Note added at 12 hrs (2011-10-30 11:37:18 GMT)
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Here's another reference: http://www.uthsc.edu/nephrology/documents/renal-syndromes-gu...
I'd go ahead with "pure primary nephrotic syndrome"
Note from asker:
Thanks for the reference info Gabrielle!
Peer comments on this reference comment:

agree SJLD
52 mins
disagree dbtrans (X) : Speaking as someone with this disease, it is minimal change nephrosis or minimal change disease
94 days
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