Glossary entry (derived from question below)
Spanish term or phrase:
no se acumuló al repetir la dosis
English translation:
did not accumulate after the repeated dose
Added to glossary by
Adam Burman
Nov 2, 2006 08:35
17 yrs ago
Spanish term
no se acumuló al repetir la dosis
Spanish to English
Medical
Medical: Pharmaceuticals
Investigator's brochure
This section deals with the "absorption" of desvenlafaxine.
Los valores de AUC en el día 14 y 1 fueron similares, lo que indica que la desvenlafaxina no se acumuló al repetir la dosis.
Los valores de AUC en el día 14 y 1 fueron similares, lo que indica que la desvenlafaxina no se acumuló al repetir la dosis.
Proposed translations
+6
5 mins
Selected
did not accumulate after the repeated dose
Pretty sure it is just this.
For example:
"Accumulation of full-length oligonucleotide after repeat dose administration is consistent with the elimination of half-lives"
from Accumulation of full-length oligonucleotide after repeat dose administration is consistent with the elimination of half-lives estimated in various tissues ...
dmd.aspetjournals.org/cgi/content/full/25/11/1272
or
The absence of accumulation in tissues was confirmed in a 90-day repeated dose study
from:
www.emea.eu.int/pdfs/vet/mrls/007496en.pdf
and many others
Good luck
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Note added at 7 mins (2006-11-02 08:43:20 GMT)
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Or "after repeating the dose"
Sentence would read:
"The AUC values on days 14 and 1 were similar, indicating that desvenlafaxine did not accumulate after repeating the dose"
For example:
"Accumulation of full-length oligonucleotide after repeat dose administration is consistent with the elimination of half-lives"
from Accumulation of full-length oligonucleotide after repeat dose administration is consistent with the elimination of half-lives estimated in various tissues ...
dmd.aspetjournals.org/cgi/content/full/25/11/1272
or
The absence of accumulation in tissues was confirmed in a 90-day repeated dose study
from:
www.emea.eu.int/pdfs/vet/mrls/007496en.pdf
and many others
Good luck
--------------------------------------------------
Note added at 7 mins (2006-11-02 08:43:20 GMT)
--------------------------------------------------
Or "after repeating the dose"
Sentence would read:
"The AUC values on days 14 and 1 were similar, indicating that desvenlafaxine did not accumulate after repeating the dose"
Peer comment(s):
agree |
Barbara Thomas
31 mins
|
Thanks
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agree |
Irina Dicovsky - MD (X)
44 mins
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Thanks Irina
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agree |
liz askew
: yes, or "after repeating the dose" as you said. I prefer this!
1 hr
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Yes, I also prefer "after repeating the dose". Thanks Liz
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agree |
Hebe Martorella
3 hrs
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Thanks again Hebe
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agree |
Roxanna Delgado
6 hrs
|
Thanks once again!
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agree |
Sonia Iujvidin
11 hrs
|
Thanks here as well Sonia
|
4 KudoZ points awarded for this answer.
Comment: "Thanks David!"
10 mins
did not get accumulated after the repetition of the dose
I would put it this way.
23 mins
did not accumulate/was not accumulative after repeat dose administration
Another way of saying it
Discussion
In the repeat dose study, a degree of drug accumulation was noted as steady state was achieved, although comparisons of C max, C min and AUC(0,12 h) after ...
www.blackwell-synergy.com/links/doi/10.1046/j.1365-2125.199... - Similar pages
File Format: PDF/Adobe Acrobat
acetaminophen may accumulate after repeated therapeutic doses in children with fever. ... differences in total AUC and t,z after the first dose .