idatrexato
English translation: edatrexate
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| 15:28 Nov 21, 2010 |
| Spanish to English translations [PRO] Medical - Patents | |||||
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|  Selected response from: liz askew United Kingdom Local time: 17:45 | ||||
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| Summary of answers provided | ||||
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| 4 | idatrexate |
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| 3 +1 | edatrexate |
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Answers
10 mins confidence: 
idatrexate Explanation: ... -------------------------------------------------- Note added at 12 mins (2010-11-21 15:41:22 GMT) -------------------------------------------------- Jul 2003... capecitabine, 5-fluorouracil, cytarabine, 2-fluorodeoxy cytidine, methotrexate, idatrexate, tomudex and trimetrexate. www.freepatentsonline.com/6586428.html analogues chosen from methotrexate, idatrexate and trimetrexate www.freepatentsonline.com/y2004/0157786.html 9 Nov 2000... from gemcitabine, capecitabine, 5 fluorouracil, cytarabine, 2fluorodeoxy cytidine, methotrexate, idatrexate, tomudex and trimetrexate. www.sumobrain.com/patents/.../WO2000066093.html |
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1 hr confidence: peer agreement (net): +1
peer agreement (net): +1edatrexate Explanation: Phase II study of carboplatin and edatrexate (10-EdAM) with ... by MH Huber - 1994 - Cited by 3 - Related articles Edatrexate is a new antifolate with improved preclinical antitumor activity when compared to methotrexate. The purpose of this study was to define the ... www.ncbi.nlm.nih.gov/pubmed/7775135 -------------------------------------------------- Note added at 1 hr (2010-11-21 16:52:31 GMT) -------------------------------------------------- New Antifolates: Pharmacology and Clinical Applications ... by CH Takimoto - 1996 - Cited by 19 - Related articles Methotrexate • Trimetrexate • Edatrexate • Piritrexim • ZD1694 • Lometrexol • AG337 • LY231514 • ... Methotrexate differs from the essential vitamin, folic acid, ...... Skin reactions induced by trimetrexate, an analog of methotrexate. ... theoncologist.alphamedpress.org/cgi/content/full/1/1/68 - Similar -------------------------------------------------- Note added at 1 hr (2010-11-21 16:53:24 GMT) -------------------------------------------------- A Structurally Altered Human Reduced Folate Carrier with Increased ... by G Jansen - 1998 - Cited by 123 - Related articles Increased Folic Acid Transport Mediates a Novel Mechanism of. Antifolate Resistance* .... methotrexate; EDX, edatrexate; TMQ, trimetrexate; PT523, Nα-(4- ... analogues such as MTX. In contrast and thus far in the human ... www.jbc.org/content/273/46/30189.full.pdf -------------------------------------------------- Note added at 1 hr (2010-11-21 16:55:57 GMT) -------------------------------------------------- http://webcache.googleusercontent.com/search?q=cache:40HBqmp... The search textbox has an autosuggest feature. When you enter three or more characters, a list of up to 10 suggestions will popup under the textbox. Use the arrow keys to move through the suggestions. To select a suggestion, hit the enter key. Using the escape key closes the listbox and puts you back at the textbox. The radio buttons allow you to toggle between having all search items start with or contain the text you entered in the search box. Search for Search text box Starts with Search item contains this Contains # A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All edatrexate A polyglutamatable folate antagonist analogue of methotrexate with antineoplastic activity. Edatrexate inhibits dihydrofolate reductase, thereby increasing cellular levels of polyglutamates, inhibiting thymidylate synthase and glycinamide ribonucleotide formyl transferase, impairing synthesis of purine nucleotides and amino acids, and resulting in tumor cell death. Edatrexate may overcome tumor resistance to methotrexate, which loses its activity after it is polyglutamated. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) -------------------------------------------------- Note added at 1 hr (2010-11-21 16:56:44 GMT) -------------------------------------------------- idatrexate not listed in the above reference |
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