non-sense mediated mRNA decay-inducing exon

03:43 Feb 21, 2020
This question was closed without grading. Reason: Answer found elsewhere

English to Russian translations [PRO]
Science - Genetics
English term or phrase: non-sense mediated mRNA decay-inducing exon
Modulating expression of SCN1A protein in a cell of the subject comprises contacting the cell of the subject with a therapeutic agent that modulates splicing of a non-sense mediated mRNA decay-inducing exon (NMD exon) from an mRNA in the cell that contains the NMD exon and encodes SCN1A, thereby modulating the level of processed mRNA encoding the SCN1A protein, and modulating expression of SCN1A protein in the cell of the subject.
oksz
Ukraine
Local time: 21:45


Summary of answers provided
4экзон, индуцирующий нонсенс-опосредованный распад мРНК
Igor Andreev
3см.
Maria Lapteva


  

Answers


4 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
non-sense mediated mrna decay-inducing exon
см.


Explanation:
экзон, индуцирующий распад мРНК, опосредованный нонсенс-кодонами.

Maria Lapteva
Serbia
Local time: 20:45
Works in field
Native speaker of: Native in RussianRussian
PRO pts in category: 4
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4 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
non-sense mediated mrna decay-inducing exon
экзон, индуцирующий нонсенс-опосредованный распад мРНК


Explanation:
Т.е. этот экзон содержит преждевременный стоп-кодон, наличие которого запускает нонсенс-опосредованный распад РНК

см.
https://elementy.ru/novosti_nauki/433459/Rasshifrovan_mekhan...

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Note added at 4 hrs (2020-02-21 07:53:14 GMT)
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https://ru.wikipedia.org/wiki/Нонсенс-опосредованный_распад

Igor Andreev
Local time: 21:45
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 112
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