gene deletion

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00:54 Mar 3, 2021
English to Croatian translations [PRO]
Medical - Medical (general)
Additional field(s): Biology (-tech,-chem,micro-), Medical: Pharmaceuticals, Genetics
English term or phrase: gene deletion
Definition from National Cancer :
The loss of all or a part of a gene. There may also be a change in the RNA and protein made from that gene. Certain gene deletions are found in cancer and in other genetic diseases and abnormalities.

Example sentence(s):
  • Gene deletions can also be applied in many different plant and human pathogenic fungi in order to decrease their pathogenicity and/or virulence for different applications. ScienceDirect
  • It is notable that targeted gene deletions generated via CRISPR/Cas9 and two guide RNAs resulted in the formation of correct junctions at high efficiency. Future Science
  • In the genomics era there is great demand for fast, simple high-throughput methods for gene deletion to study the roles of the large numbers of genes that are being identified. PubMed
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Summary of translations provided
4genska delecija
drazenborcic


  

Translations offered


3 days 7 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
genska delecija


Definition from own experience or research:
Vrsta genske mutacije kod koje se gubi dio DNA (ili RNA kod RNA organizama).

Example sentence(s):
  • Insercija (adicija) je umetanje jednog ili dva nukleotida; delecija je gubitak jednog ili dva nukleotida. Insercija i delecija uzrokuju FRAME-SHIFT MUTACIJU ili POMAK OKVIRA ČITANJA. - Online Texbook  

Explanation:
"Gene" u izvorniku naglašava da se radi o genskoj deleciji, a ne kromosomskoj deleciji (vidi https://www.enciklopedija.hr/natuknica.aspx?ID=42586) gdje se gubi dio kromosoma s većim brojem gena. Pridjev "genska" može se izostaviti jer se, ako se ne naglasi da se misli na kromosomsku deleciju, podrazumijeva da se radi o genskoj mutaciji.
drazenborcic
Local time: 15:33
Native speaker of: Croatian
PRO pts in category: 68
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